Publications

Dormoy-Raclet V, Markovits J, Malato Y, Huet S, Lagarde P, Montaudon D, Jacquemin-Sablon A, Jacquemin-Sablon H.  2007.  Unr, a cytoplasmic RNA-binding protein with cold-shock domains, is involved in control of apoptosis in ES and HuH7 cells. Oncogene. 26:2595-605. Abstract

Castera L.  2009.  Transient elastography and other noninvasive tests to assess hepatic fibrosis in patients with viral hepatitis. J Viral Hepat. 16:300-14. Abstract

Varon C, Tatin F, Moreau V, Van Obberghen-Schilling E, Fernandez-Sauze S, Reuzeau E, Kramer I, Genot E.  2006.  Transforming growth factor beta induces rosettes of podosomes in primary aortic endothelial cells. Mol Cell Biol. 26:3582-94. Abstract

Boyault S, Rickman DS, de Reynies A, Balabaud C, Rebouissou S, Jeannot E, Herault A, Saric J, Belghiti J, Franco D et al..  2007.  Transcriptome classification of HCC is related to gene alterations and to new therapeutic targets. Hepatology. 45:42-52. Abstract

De Ledinghen V, Monvoisin A, Neaud V, Krisa S, Payrastre B, Bedin C, Desmouliere A, Bioulac-Sage P, Rosenbaum J.  2001.  Trans-resveratrol, a grapevine-derived polyphenol, blocks hepatocyte growth factor-induced invasion of hepatocellular carcinoma cells. Int J Oncol. 19:83-8. Abstract

Villeneuve J, Block A, Le Bousse-Kerdiles MC, Lepreux S, Nurden P, Ripoche J, Nurden AT.  2009.  Tissue inhibitors of matrix metalloproteinases in platelets and megakaryocytes: a novel organization for these secreted proteins. Exp Hematol. 37:849-56. Abstract

Neaud V, Duplantier JG, Mazzocco C, Kisiel W, Rosenbaum J.  2004.  Thrombin up-regulates tissue factor pathway inhibitor-2 synthesis through a cyclooxygenase-2-dependent, epidermal growth factor receptor-independent mechanism. J Biol Chem. 279:5200-6. Abstract

Gillibert-Duplantier J, Neaud V, Blanc JF, Bioulac-Sage P, Rosenbaum J.  2007.  Thrombin inhibits migration of human hepatic myofibroblasts. Am J Physiol Gastrointest Liver Physiol. 293:G128-36. Abstract

Rottiers P, Saltel F, Daubon T, Chaigne-Delalande B, Tridon V, Billottet C, Reuzeau E, Genot E.  2009.  TGF -induced endothelial podosomes mediate basement membrane collagen degradation in arterial vessels. Journal of Cell Science. 122(23):4311-4318. Abstract

Varon C, Basoni C, Reuzeau E, Moreau V, Kramer IJ, Genot E.  2006.  TGFbeta1-induced aortic endothelial morphogenesis requires signaling by small GTPases Rac1 and RhoA. Exp Cell Res. 312:3604-19. Abstract

Varon C, Rottiers P, Ezan J, Reuzeau E, Basoni C, Kramer I, Genot E.  2008.  TGFbeta1 regulates endothelial cell spreading and hypertrophy through a Rac-p38-mediated pathway. Biol Cell. 100:537-50. Abstract

Guyot C, Combe C, Clouzeau-Girard H, Moronvalle-Halley V, Desmouliere A.  2007.  Specific activation of the different fibrogenic cells in rat cultured liver slices mimicking in vivo situations. Virchows Arch. 450:503-12. Abstract

Mazella J, Pétrault O, Lucas G, Deval E, Béraud-Dufour S, Gandin C, El-Yacoubi M, Widmann C, Guyon A, Chevet E et al..  2010.  Spadin, a Sortilin-Derived Peptide, Targeting Rodent TREK-1 Channels: A New Concept in the Antidepressant Drug Design. PLoS Biology. 8(4):e1000355. Abstract

Yi P, Higa A, Taouji S, Bexiga MG, Marza E, Arma D, Castain C, Le Bail B, Simpson J, Rosenbaum J et al..  2012.  Sorafenib-mediated targeting of the AAA+ ATPase p97/VCP leads to disruption of the secretory pathway, endoplasmic reticulum stress and hepatocellular cancer cell death.. Molecular cancer therapeutics. Abstract

Llovet JM, Ricci S, Mazzaferro V, Hilgard P, Gane E, Blanc JF, de Oliveira AC, Santoro A, Raoul JL, Forner A et al..  2008.  Sorafenib in advanced hepatocellular carcinoma. N Engl J Med. 359:378-90. Abstract

Pilati C, Amessou M, Bihl MP, Balabaud C, Van Nhieu JT, Paradis V, Nault JC, Izard T, Bioulac-Sage P, Couchy G et al..  2011.  Somatic mutations activating STAT3 in human inflammatory hepatocellular adenomas. Journal of Experimental Medicine. 208(668932323254529112661614395143715772267205211193251553):1359-1366. Abstract

Tatin F, Grise F, Reuzeau E, Genot E, Moreau V.  2010.  Sodium fluoride induces podosome formation in endothelial cells. Biology of the Cell. Abstract

Bouchecareilh M, Marza E, Caruso M-E, Chevet E.  2011.  Small GTPase Signaling and the Unfolded Protein Response. 491:343-360. Abstract

Tatin F, Varon C, Genot E, Moreau V.  2006.  A signalling cascade involving PKC, Src and Cdc42 regulates podosome assembly in cultured endothelial cells in response to phorbol ester. J Cell Sci. 119:769-81. Abstract

Higa A, Mulot A, Delom F, Bouchecareilh M, Nguyen DT, Boismenu D, Wise MJ, Chevet E.  2011.  Role of the pro-oncogenic Protein Disulfide Isomerase (PDI)-family member Anterior Gradient 2 (AGR2) in the control of Endoplasmic Reticulum homeostasis. Journal of Biological Chemistry. Abstract

Duplantier JG, Dubuisson L, Senant N, Freyburger G, LAURENDEAU I, Herbert JM, Desmouliere A, Rosenbaum J.  2004.  A role for thrombin in liver fibrosis. Gut. 53:1682-7. Abstract

Grise F, Sena S, Bidaud-Meynard A, Baud J, Hiriart J-B, Makki K, Dugot-Senant N, Staedel C, Bioulac-Sage P, Zucman-Rossi J et al..  2012.  Rnd3/RhoE is down-regulated in hepatocellular carcinoma and controls cellular invasion. Hepatology. 55:1766-1775. Abstract

Chaigne-Delalande B, Deuve L, Reuzeau E, Basoni C, Lafarge D, Varon C, Tatin F, Anies G, Garand R, Kramer I et al..  2006.  RhoGTPases and p53 are involved in the morphological appearance and interferon-alpha response of hairy cells. Am J Pathol. 168:562-73. Abstract

Grise F, Bidaud A, Moreau V.  2009.  Rho GTPases in hepatocellular carcinoma. Biochim Biophys Acta. 1795:137-51. Abstract

Billottet C, Rottiers P, Tatin F, Varon C, Reuzeau E, Maitre JL, Saltel F, Moreau V, Genot E.  2008.  Regulatory signals for endothelial podosome formation. Eur J Cell Biol. 87:543-54. Abstract